USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: P55809 USC-OGP 2-DE database:  P55809 P55809 General information about the entry View entry in simple text format Entry name SCOT1_HUMAN Primary accession number P55809 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial; EC=2.8.3.5; AltName: Full=3-oxoacid CoA-transferase 1; AltName: Full=Somatic-type succinyl-CoA:3-oxoacid CoA-transferase; Short=SCOT-s; Flags: Precursor;. Gene name Name=OXCT1 Synonyms=OXCT, SCOT Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1148: pI=6.34; Mw=55360 Cross-references UniProtKB/Swiss-Prot P55809; SCOT1_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name SCOT1_HUMAN Primary accession number P55809 Secondary accession number(s) B2R5V2 B7Z528 Sequence was last modified on  November 1, 1997 (version 1) Annotations were last modified on  March 15, 2017 (version 165) Name and origin of the protein Description RecName: Full=Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial; EC=2.8.3.5; AltName: Full=3-oxoacid CoA-transferase 1; AltName: Full=Somatic-type succinyl-CoA:3-oxoacid CoA-transferase; Short=SCOT-s; Flags: Precursor; Gene name Name=OXCT1 Synonyms=OXCT, SCOT Encoded on Name=OXCT1; Synonyms=OXCT, SCOT Keywords 3D-structure; Alternative splicing; Complete proteome; Direct protein sequencing; Disease mutation; Mitochondrion; Phosphoprotein; Polymorphism; Reference proteome; Transferase; Transit peptide. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL U62961; AAB07366.1; -; mRNA EMBL AB029576; BAB13733.1; -; Genomic_DNA EMBL AK298352; BAH12764.1; -; mRNA EMBL AK312327; BAG35249.1; -; mRNA EMBL AK315902; BAH14273.1; -; mRNA EMBL AC008817; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL AC034222; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL AC114946; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL BC009001; AAH09001.1; -; mRNA CCDS CCDS3937.1; -. [P55809-1]; . RefSeq NP_000427.1; NM_000436.3. [P55809-1]; . UniGene Hs.278277; -; . PDB 3DLX; X-ray; 2.20 A; A/B/C/D=40-520 PDBsum 3DLX; -; . ProteinModelPortal P55809; -; . SMR P55809; -; . BioGrid 111059; 64; . IntAct P55809; 5; . STRING 9606.ENSP00000196371; -; . DrugBank DB02731; Ethylmercurithiosalicylic acid; . DrugBank DB00139; Succinic acid; . iPTMnet P55809; -; . PhosphoSitePlus P55809; -; . BioMuta OXCT1; -; . DMDM 2492998; -; . UCD-2DPAGE P55809; -; . EPD P55809; -; . MaxQB P55809; -; . PaxDb P55809; -; . PeptideAtlas P55809; -; . PRIDE P55809; -; . DNASU 5019; -; . Ensembl ENST00000196371; ENSP00000196371; ENSG00000083720. [P55809-1]; . Ensembl ENST00000510634; ENSP00000423144; ENSG00000083720. [P55809-2]; . Ensembl ENST00000512084; ENSP00000421143; ENSG00000083720. [P55809-2]; . GeneID 5019; -; . KEGG hsa:5019; -; . UCSC uc003jmn.4; human. [P55809-1]; . CTD 5019; -; . DisGeNET 5019; -; . GeneCards OXCT1; -; . HGNC HGNC:8527; OXCT1; . HPA HPA012047; -; . HPA HPA061425; -; . MalaCards OXCT1; -; . MIM 245050; phenotype; . MIM 601424; gene; . neXtProt NX_P55809; -; . OpenTargets ENSG00000083720; -; . Orphanet 832; Succinyl-CoA:3-ketoacid CoA transferase deficiency; . PharmGKB PA32855; -; . eggNOG KOG3822; Eukaryota; . eggNOG COG1788; LUCA; . eggNOG COG2057; LUCA; . GeneTree ENSGT00390000009130; -; . HOGENOM HOG000221245; -; . HOVERGEN HBG002310; -; . InParanoid P55809; -; . KO K01027; -; . OMA NIQFRHA; -; . OrthoDB EOG091G0D3X; -; . PhylomeDB P55809; -; . TreeFam TF313991; -; . BioCyc MetaCyc:HS01447-MONOMER; -; . BRENDA 2.8.3.5; 2681; . Reactome R-HSA-77108; Utilization of Ketone Bodies; . UniPathway UPA00929; UER00894; . EvolutionaryTrace P55809; -; . GeneWiki OXCT1; -; . GenomeRNAi 5019; -; . PRO PR:P55809; -; . Proteomes UP000005640; Chromosome 5; . Bgee ENSG00000083720; -; . CleanEx HS_OXCT1; -; . ExpressionAtlas P55809; baseline and differential; . Genevisible P55809; HS; . GO GO:0005759; C:mitochondrial matrix; TAS:Reactome; . GO GO:0005739; C:mitochondrion; IDA:UniProtKB; . GO GO:0005654; C:nucleoplasm; IDA:HPA; . GO GO:0008260; F:3-oxoacid CoA-transferase activity; IMP:UniProtKB; . GO GO:0042803; F:protein homodimerization activity; NAS:UniProtKB; . GO GO:0060612; P:adipose tissue development; IEA:Ensembl; . GO GO:0007420; P:brain development; IEA:Ensembl; . GO GO:0046950; P:cellular ketone body metabolic process; IMP:UniProtKB; . GO GO:0007507; P:heart development; IEA:Ensembl; . GO GO:0046952; P:ketone body catabolic process; TAS:Reactome; . GO GO:0042182; P:ketone catabolic process; IEA:Ensembl; . GO GO:0035774; P:positive regulation of insulin secretion involved in cellular response to glucose stimulus; IEA:Ensembl; . GO GO:0014823; P:response to activity; IEA:Ensembl; . GO GO:0042493; P:response to drug; IEA:Ensembl; . GO GO:0045471; P:response to ethanol; IEA:Ensembl; . GO GO:0009725; P:response to hormone; IEA:Ensembl; . GO GO:0007584; P:response to nutrient; IEA:Ensembl; . GO GO:0042594; P:response to starvation; IEA:Ensembl; . InterPro IPR012792; 3-oxoacid_CoA-transf_A; . InterPro IPR012791; 3-oxoacid_CoA-transf_B; . InterPro IPR014388; 3-oxoacid_CoA-transferase; . InterPro IPR004165; CoA_trans_fam_I; . InterPro IPR004164; CoA_transf_AS; . InterPro IPR004163; CoA_transf_BS; . PANTHER PTHR13707; PTHR13707; 1; . Pfam PF01144; CoA_trans; 2; . PIRSF PIRSF000858; SCOT-t; 1; . SMART SM00882; CoA_trans; 2; . TIGRFAMs TIGR02429; pcaI_scoA_fam; 1; . TIGRFAMs TIGR02428; pcaJ_scoB_fam; 1; . PROSITE PS01273; COA_TRANSF_1; 1; . PROSITE PS01274; COA_TRANSF_2; 1; .

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• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
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